RuO2

Materials

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BET
b nanozyme
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868RuO22nmTEMthe mean diameter of the RuO2NPs was ∼2 nm, and the hydrodynamic size of RuO2NPs was about 5.4 nm
688RuO228nmTEMThe nanoparticles aggregate randomly to form almost spherical shape with an average diameter of 28 nm, which is as per the TEM analysis.64.5

Kinetics

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comment
688RuO2688
868RuO2CATH2O23.59mM2.29mM/min868
975RuO2CATH2O20.843M10.7mg L-1 S- 1mM/min975
977RuO2CATH2O20.843M10.7mg L-1 S- 1mM/min977
977RuO2PODTMB75.6mM0.753μM/s977

Applications

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688RuO2detection of H2O2H2O2Color10-600μM
868RuO2The NP catalytic properties mimic the activity of catalase, peroxidase, superoxide dismutase, and glutathione peroxidase. The nanozyme can be efficiently and rapidly absorbed by human embryonic kidney cells while significantly reducing ROS-induced apoptosis by eliminating excess ROS. After intravenous injection, the ultrasmall RuO2NPs significantly inhibit the development of AKI in mice. In vivo toxicity experiments demonstrate the biosafety of the NPs after long-term preventing.ROS
975RuO2Oxidative stress related disease treatment
977RuO2Oxidative stress related disease treatment

References

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title
DOI
material type
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688Efficient multifunctional catalytic and sensing properties of synthesized ruthenium oxide nanoparticleshttps://doi.org/10.3390/catal10070780Metal oxideEfficient Multifunctional Catalytic and Sensing Properties of Synthesized Ruthenium Oxide Nanoparticles
868An Ultrasmall RuO2 Nanozyme Exhibiting Multienzyme-like Activity for the Prevention of Acute Kidney Injuryhttps://doi.org/10.1021/acsami.0c07886Metal oxidethe ultrasmall RuO2NPs promising as a nanozyme for the prevention of AKI