Biomimetic Platinum Nanozyme Immobilized on 2D Metal–Organic Frameworks for Mitochondrion-Targeting and Oxygen Self-Supply Photodynamic Therapy

References

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title
DOI
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44Biomimetic Platinum Nanozyme Immobilized on 2D Metal–Organic Frameworks for Mitochondrion-Targeting and Oxygen Self-Supply Photodynamic Therapyhttps://doi.org/10.1021/acsami.9b14958Compositea new two-dimensional (2D)metal−organic framework, Sm-tetrakis(4-carboxyphenyl)porphyrin (TCPP) nanosheets,by assembling transition metal ions (Sm3+) and PSs (TCPP), on which the catalase (CAT)-mimicking platinum nanozymes were then in situ grown for sufficient oxygen supply during PDT

Materials

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size
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size type
size comment
BET
b nanozyme
b 10n
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specific act
sa 10n
sa unit
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44Sm-TCPP-PtnmTEMnanoplate morphology (∼100 nm in diameter) and ultrathin thickness (<10 nm)

Kinetics

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T
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vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
44Sm-TCPP-PtH2O24444

Applications

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target
method
linear range
linear ran unit
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recovery
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44Sm-TCPP-Ptgenerating oxygen for PDTH2O2