Label-free homogeneous electrochemical detection of MicroRNA based on target-induced anti-shielding against the catalytic activity of two-dimension nanozyme

References

Loading, please wait
ref
title
DOI
material type
comment
317Label-free homogeneous electrochemical detection of MicroRNA based on target-induced anti-shielding against the catalytic activity of two-dimension nanozymehttps://doi.org/10.1016/j.bios.2020.112707Metal oxideHerein, a soft template-directed wet chemical approach was proposed for preparation of 2D MnO2 nanoflakes, in which the morphology can be easily tuned by the template dosage.

Materials

Loading, please wait
ref
material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
3172D MnO2 nanoflakes300*5nmTEMThe lateral dimension and thickness of 2D MnO2 nanoflakes were calculated to be 300 nm and 5 nm, respec

Kinetics

Loading, please wait
ref
material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
3172D MnO2 nanoflakesPODTMB/OPD/ABTS,317

Applications

Loading, please wait
ref
material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
3172D MnO2 nanoflakesdetect microRNALet-7aE-chem0.4 to 100nM250pM105.4%, 96.3%, and 102.1%