A thiamine-triggered fluormetric assay for acetylcholinesterase activity and inhibitor screening based on oxidase-like activity of MnO2 nanosheets

References

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title
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623A thiamine-triggered fluormetric assay for acetylcholinesterase activity and inhibitor screening based on oxidase-like activity of MnO2 nanosheetshttps://doi.org/10.1016/j.talanta.2020.121362Compositemanganese dioxide nanosheets (MnO2 NSs)

Materials

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size
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BET
b nanozyme
b 10n
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623MnO2 NSsnmTEMAs presented in Fig. 1A, the synthetic MnO2 NSs exhibited an ultrathin 2D sheetlike structure.

Kinetics

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vmax 10n
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623thiamine-MnO2OXDATCh623623

Applications

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linear range
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623thiamine-MnO2A thiamine-triggered fluormetric assay for acetylcholinesterase activity and inhibitor screeningacetylcholinesterase (AChE)Fluor0.02-1mU/mL15μU/mL