Biphasic Synthesis of Biodegradable Urchin-Like Mesoporous Organosilica Nanoparticles for Enhanced Cellular Internalization and Precision Cascaded Therapy

References

Loading, please wait
ref
title
DOI
material type
comment
1201Biphasic Synthesis of Biodegradable Urchin-Like Mesoporous Organosilica Nanoparticles for Enhanced Cellular Internalization and Precision Cascaded Therapyhttps://doi.org/10.1039/d1bm00015bCompositeTME-responsive ultrasmall gold-capped UMONs (UMONs–Au) through ion–ligand interactions between amino group-functionalized UMONs (UMONs–NH2) and l-cysteine-derived ultrasmall gold nanoparticles (AuNPs–Cys) with bridged ferrous ions

Materials

Loading, please wait
ref
material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
1201UMONs-LA-Au2.4nmTEMAfter ultrasmall gold capping, the average pore size of UMONs–Au was decreased to approximately 2.4 nm, accompanied by the decrease of BET surface area from 873.2 m2 g−1 to 489.5 m2 g−1489.5

Kinetics

Loading, please wait
ref
material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
1201UMONs-LA-AuLA–H2O2371201

Applications

Loading, please wait
ref
material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
1201UMONs-LA-Aupromoted the oxidation of LA for an improved NO yield, which led to significant nanocatalysis-enhanced NO gas therapy for tumor eradication