Colorimetric acid phosphatase sensor based on MoO3 nanozyme

References

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173Colorimetric acid phosphatase sensor based on MoO3 nanozymehttps://doi.org/10.1016/j.aca.2020.01.035Metal oxidemolybdenum oxide nanoparticles (MoO3 NPs).

Materials

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BET
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173MoO3 NPs2-4nmTEMThe TEM image in Fig. 1A shows that the MoO3 NPs are well dispersed with an average diameter of 2.0e4.0 nm. The lattice spacing of 0.21 nm in the HRTEM image

Kinetics

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173MoO3 NPsOXDABTS1.6769mM173

Applications

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linear range
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173MoO3 NPsAcid phosphatase (ACP) catalyzes the hydrolysis of the ascorbic acid 2-phosphate (AAP) substrate to produce ascorbic acid (AA). AAwas found to fade the coloration process of the MoO3 NP-mediated ABTS oxidation. By combining the oxidase-mimicking property of the MoO3 NPs and the ACP-catalyzed hydrolysis ofAAP, a novel and simple colorimetric method for detecting ACP was establishedAcid phosphatase (ACP)Color0.09-7.3U/L0.011U/L92-107.6%