Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease model

References

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title
DOI
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77Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease modelhttps://doi.org/10.1016/j.biomaterials.2019.119752CompositeTPP-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] functionalized molybdenum disulfide quantum dots (TPP-MoS2 QDs)

Materials

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material
size
size err
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BET
b nanozyme
b 10n
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specific act
sa 10n
sa unit
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77TPP-MoS2 QDs50nmTEMthe lateral diameters
77TPP-MoS2 QDs1.690.15nmTEMthe thicknesses

Kinetics

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substrate
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T
km
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vmax
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vmax 10n
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kcat
kcat err
kcat 10n
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kcat/km 10n
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comment
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Applications

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target
method
linear range
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77TPP-MoS2 QDsmitigate AD pathologyO2•- •OH H2O2