Self-assembled chromogen-loaded polymeric cocoon for respiratory virus detection

References

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1165Self-assembled chromogen-loaded polymeric cocoon for respiratory virus detectionhttps://doi.org/10.1039/D0NR06893DMetalcopper nanoflowers (CuNFs)

Materials

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BET
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1165CuNFs400-500nmSEMThe SEM image in Fig. 1h shows the flower-like structures of CuNFs with an average size of 400–500 nm, having hierarchical structures with high surface-to-volume ratios.

Kinetics

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1165CuNFsPODTMB0.07mM0.12-3mM/s1165
1165CuNFsPODH2O26.5mM0.02-3mM/s1165

Applications

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1165CuNFsimmunoassay demonstrates high sensitivity for IV/Ainfluenza virus (IV)/A10–10*6fg mL−132.37fg mL−1a limit of detection (LOD) as low as 32.37 fg mL−1 and 54.97 fg mL−1 in buffer and serum, respectively. For practical needs, a clinically isolated IV/A/H3N2 and spike protein of SARS-CoV-2 were detected with the LODs of 17 pfu mL−1 and 143 fg mL−1, respectively.