ref | title | DOI | material type | comment |
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868 | An Ultrasmall RuO2 Nanozyme Exhibiting Multienzyme-like Activity for the Prevention of Acute Kidney Injury | https://doi.org/10.1021/acsami.0c07886 | Metal oxide | the ultrasmall RuO2NPs promising as a nanozyme for the prevention of AKI |
ref | material | application | target | method | linear range | linear ran unit | LOD | lod unit | recovery | comment |
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868 | RuO2 | The NP catalytic properties mimic the activity of catalase, peroxidase, superoxide dismutase, and glutathione peroxidase. The nanozyme can be efficiently and rapidly absorbed by human embryonic kidney cells while significantly reducing ROS-induced apoptosis by eliminating excess ROS. After intravenous injection, the ultrasmall RuO2NPs significantly inhibit the development of AKI in mice. In vivo toxicity experiments demonstrate the biosafety of the NPs after long-term preventing. | ROS |