Nanoceria-Based Phospholipase-Mimetic Cell Membrane Disruptive Antibiofilm Agents

References

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title
DOI
material type
comment
1378Nanoceria-Based Phospholipase-Mimetic Cell Membrane Disruptive Antibiofilm Agentshttps://doi.org/10.1021/acsabm.0c00363Compositepolymer-coated nanoceria (PAA-Cnp)

Materials

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material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
1378PAA-Cnp10nmTEMThe scanning electron microscopy (SEM) images of the nanomaterials showed agglomerated particles, which upon sonication in acetone revealed a particle-like morphology (size ∼10 nm) in the transmission electron microscopy (TEM) images

Kinetics

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material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
1378CnphydrolaseNPPC7.8379.80.25mM45684µM/h13781378
1378PAA-CnphydrolaseNPPC7.837171.81.89mM49268.4µM/h13781378

Applications

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material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
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1378PAA-Cnpmembrane disruption-based bactericidal activity against a broad spectrum of pathogenic as well as biofilm-encased bacteria