A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level

References

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835A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance levelhttps://doi.org/10.1016/j.bios.2020.112325CompositeGold-viral biomineralized nanoclusters (AuVCs)

Materials

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BET
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835AuVCs26.50.80nmTEMThe morphology of VLPs and AuVCs were first characterized using transmission electron microscopy (TEM); no obvious difference in morphology was observed between them, but the diameter of the AuVCs was slightly decreased to 26.50 ± 0.80 nm compared with VLPs (28.90 ± 0.90 nm).

Kinetics

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835AuVCsPODTMB41.674.51μM5.750.43μM/min835

Applications

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835AuVCsDetection of GSHGSHColor25–500μM9.8μM99.64–104.71%The easy-to-use LFPB with smartphone could achieve a limit of detection of 9.8 μM and a wide range of 25–500 μM for GSH.