Stimuli-Responsive Manganese Single-Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactions

References

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ref
title
DOI
material type
comment
1107Stimuli-Responsive Manganese Single-Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactionshttps://doi.org/10.1002/anie.202017152Single-atomPEGylated manganese-based SAE (Mn/PSAE)

Materials

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material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
1107Mn/PSAE230nmSEMFirst, ZIF-8 nanocubes (ZIF-8 NCs), with average particle size of about 230 nm (Supporting Information, Figure S1), were etched with tannic acid (TA) in aqueous solution to generate a hollow structure by a controlled chemical etching approach.1298

Kinetics

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material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
1107Mn/PSAEPODTMB6250.14mM30-8M/s11071107
1107Mn/PSAEOXDTMB6250.11mM7-8M/s11071107
1107Mn/PSAEPODH2O26250.09mM16-8M/s11071107

Applications

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ref
material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
1107Mn/PSAETumor Therapy via Integrated Cascade Reactions