Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy

References

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ref
title
DOI
material type
comment
38Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapyhttps://doi.org/10.1126/sciadv.abb2695Compositean integrated SOD/CAT mimetic cascade nanozyme (designated as Pt@PCN222-Mn) by introducing an SOD-like moiety of Mn(III) porphyrin and a CAT-like Pt NP within a nanoscale Zr-based MOF, PCN222

Materials

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ref
material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
38Pt@PCN222-Mn200nmTEM

Kinetics

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material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
38Pt@PCN223-MnCATH2O23838
38Pt@PCN222-MnSOD•O2−3838

Applications

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ref
material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
38Pt@PCN222-MnROS scavenge•O2−