Near‐Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple‐Therapy for Combating Multidrug‐Resistant Bacterial Infections via Oxygen‐Vacancy Molybdenum Trioxide Nanodots

References

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618Near‐Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple‐Therapy for Combating Multidrug‐Resistant Bacterial Infections via Oxygen‐Vacancy Molybdenum Trioxide Nanodotshttps://doi.org/10.1002/smll.202005739Metal oxideoxygen-vacancy molybdenum trioxide nanodots (MoO3−x NDs)

Materials

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618MoO3−x NDsThe typical transmission electron microscopy (TEM) image of the as-obtained supernatant (Figure 1A) showed well-dispersed nanodots with an average diameter of 3.07 ± 0.35 nm (Figure 1B) as calculated from counting 80 particles of the TEM images. The high-resolution TEM (HRTEM) characterization showed the lattice spacings of about 0.231 nm in the crystal structure of the nanodots, which was consistent well with the (224) diffraction planes of MoO3 (JCPDS No. 21-0569). As indicated in the Figure 1C, the atomic force microscope (AFM) image with the height analysis (inset of Figure 1C) confirmed the good mono-dispersibility of the nanodots. The average height was 1.43 ± 0.08 nm,

Kinetics

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618MoO3−x NDsPODTMB2.65mM0.0152-7M/s618618
618MoO3−x NDsPODH2O20.26mM1.52-7M/s618618

Applications

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618MoO3−x NDsNear-Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple-Therapy for Combating Multidrug-Resistant Bacterial Infections