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A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy
References
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ref
title
DOI
material type
comment
82
A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy
https://doi.org/10.1016/j.nantod.2020.100935
Carbon
phosphorous and nitrogen dual-doped porous hollow carbon sphere
Materials
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ref
material
size
size err
size unit
size type
size comment
BET
b
nanozyme
b
10
n
b
unit
specific act
sa 10
n
sa unit
comment
82
PNCNzyme
100
10
nm
TEM
uniform size of approximately 100 ± 10 nm in diameterwith hollow and porous structure
Kinetics
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ref
material
enzyme type
substrate
pH
T
k
m
k
m
err
k
m
10
n
k
m
unit
v
max
v
max
err
v
max
10
n
v
max
unit
k
cat
k
cat
err
k
cat
10
n
k
cat
unit
k
cat
/
k
m
k
cat
/
k
m
10
n
k
cat
/
k
m
unit
comment
82
PNCNzyme
POD
H2O2
154.8
mM
54.22
-8
M/s
82
82
82
PNCNzyme
POD
TMB
0.07915
mM
22.82
-8
M/s
82
82
Applications
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ref
material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
82
PNCNzyme
Activating IAA to produce abundant ROS and triggering tumor cell apo-ptosis
Nanozyme Database