ref | title | DOI | material type | comment |
---|---|---|---|---|
106 | Immunomodulation‐Enhanced Nanozyme‐Based Tumor Catalytic Therapy | https://doi.org/10.1002/adma.202003563 | Composite | TGF-β inhibitor (TI)-loaded PEGylated iron manganese silicate nanoparticles (IMSN) (named as IMSN-PEG-TI) are constructed to trigger the therapeutic modality. |
ref | material | size | size err | size unit | size type | size comment | BET | b nanozyme | b 10n | b unit | specific act | sa 10n | sa unit | comment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
106 | IMSN-PEG-TI | 100 | nm | TEM | The typical transmission electron microscopy (TEM) and scanning electron microscopy (SEM) images indicated the as-prepared IMSN exhibited a uniform spherical morphology with an average diameter of about100 nm, and the surface of IMSN became rough (Figure 1b,c). |
ref | material | enzyme type | substrate | pH | T | km | km err | km 10n | km unit | vmax | vmax err | vmax 10n | vmax unit | kcat | kcat err | kcat 10n | kcat unit | kcat/km | kcat/km
10n | kcat/km unit | comment |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
106 | IMSN-PEG-TI | POD | H2O2 | 49.8 | -3 | M | 5.283 | -8 | M/s | 106 | 106 |
ref | material | application | target | method | linear range | linear ran unit | LOD | lod unit | recovery | comment |
---|---|---|---|---|---|---|---|---|---|---|
106 | IMSN-PEG-TI | The results show that IMSN nanozyme exhibits both intrinsic peroxidase-like and catalase-like activities under acidic TME, which can decompose H2O2 into hydroxyl radicals (•OH) and oxygen (O2), respectively |