| 7992 |
781 |
PtDENs |
21.2 |
0.7 |
nm |
DLS |
Moreover, the size of mAb-PtDEN-GOD (34.3 ± 1.6 nm) (Fig. 1f, bottom) was obviously more than that of PtDENs (21.2 ± 0.7 nm) (Fig. 1f, top) on the basis of DLS data |
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| 7991 |
781 |
mAb-PtDEN-GOD |
34.3 |
1.6 |
nm |
DLS |
Moreover, the size of mAb-PtDEN-GOD (34.3 ± 1.6 nm) (Fig. 1f, bottom) was obviously more than that of PtDENs (21.2 ± 0.7 nm) (Fig. 1f, top) on the basis of DLS data |
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| 7990 |
781 |
PtNPs |
2.3 |
|
nm |
TEM |
Figure 1c shows high-resolution transmission electron microscope (HRTEM) of the as-synthesized PtDENs. It is found that many PtNPs were distributed in the dendrimers, and the average size of nanoparticles was ~ 2.3 nm in diameter. |
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| 7989 |
781 |
mAb-PtDEN-GOD |
28 |
|
nm |
TEM |
To tackle this shortcoming, the as-prepared mAb-PtDEN-GOD conjugates were characterized by TEM after negative staining with sodium phosphotungstate (2.0 wt%, pH 7.3) (note: not good for negative staining of dendrimers). As seen from Fig. 1d, a layer of translucent structures was coated on the nearly spherical dendrimers, and the mean size was ~ 28 nm in diameter. |
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