IMSN-PEG-TI

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7405 106 IMSN-PEG-TI 100 nm TEM The typical transmission electron microscopy (TEM) and scanning electron microscopy (SEM) images indicated the as-prepared IMSN exhibited a uniform spherical morphology with an average diameter of about100 nm, and the surface of IMSN became rough (Figure 1b,c).

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
5992 106 IMSN-PEG-TI POD H2O2 49.8 -3 M 5.283 -8 M/s 106 106

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5010 106 IMSN-PEG-TI The results show that IMSN nanozyme exhibits both intrinsic peroxidase-like and catalase-like activities under acidic TME, which can decompose H2O2 into hydroxyl radicals (•OH) and oxygen (O2), respectively

References

ref title DOI material type comment
3337 106 Immunomodulation‐Enhanced Nanozyme‐Based Tumor Catalytic Therapy https://doi.org/10.1002/adma.202003563 Composite TGF-β inhibitor (TI)-loaded PEGylated iron manganese silicate nanoparticles (IMSN) (named as IMSN-PEG-TI) are constructed to trigger the therapeutic modality.