MIL-101(Fe)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7460 168 MIL-101(Fe) 500 nm SEM SEM images showed that MIL-101(Fe) had the well-defined octahedral morphology with an average diagonal length of approximately 500 nm 2702.9
7776 546 MIL-101(Fe) 600-800 nm TEM 5

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6058 168 MIL-101(Fe) POD TMB 4.0 55 0.585 mM 10.083 -7 M/s 168
6059 168 MIL-101(Fe) POD H2O2 4.0 55 0.043 mM 5.138 -7 M/s 168 168
6419 546 MIL-101(Fe) POD H2O2 1.8 mM 4.53 -7 M/s 546 546
6420 546 MIL-101(Fe) POD TMB 6.71 mM 6.01 -7 M/s 546 546

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5076 168 MIL-101(Fe) According to the enzyme cascade amplification strategy, the MIL-101(Fe) nanozyme in conjunction with AChE and ChOx provided a novel label-free fluorescent assay for detection of choline and ACh with high selectivity and sensitivity. Given this, this proposed sensing strategy was successfully utilized to detect the choline in milk and ACh in human plasma with desirable results H2O2 Fluor 0.1-130 μM 1.1 nM
5077 168 MIL-101(Fe) According to the enzyme cascade amplification strategy, the MIL-101(Fe) nanozyme in conjunction with AChE and ChOx provided a novel label-free fluorescent assay for detection of choline and ACh with high selectivity and sensitivity. Given this, this proposed sensing strategy was successfully utilized to detect the choline in milk and ACh in human plasma with desirable results Ach Fluor 0.1-100 μM 8.9 nM
5078 168 MIL-101(Fe) According to the enzyme cascade amplification strategy, the MIL-101(Fe) nanozyme in conjunction with AChE and ChOx provided a novel label-free fluorescent assay for detection of choline and ACh with high selectivity and sensitivity. Given this, this proposed sensing strategy was successfully utilized to detect the choline in milk and ACh in human plasma with desirable results choline Fluor 0.05-10 μM 20 nM

References

ref title DOI material type comment
3399 168 A label-free fluorescence biosensor based on a bifunctional MIL-101 (Fe) nanozyme for sensitive detection of choline and acetylcholine at nanomolar level https://doi.org/10.1016/j.snb.2020.128021 MOF MIL-101(Fe)
3733 546 Tuning Atomically Dispersed Fe Sites in Metal–Organic Frameworks Boosts Peroxidase-Like Activity for Sensitive Biosensing https://doi.org/10.1007/s40820-020-00520-3 MOF MIL-101(Fe)