PEG-Au/FeMOF@CPT NPs

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7670 440 PEG-Au/FeMOF@CPT NPs 50 nm TEM Monodispersed nanoparticles with the diameter around 50 nm were observed in transmission electron microscopy (TEM) image (Figure 1a and Figure S1, Supporting Information). Au/FeMOF NPs were further fabricated using FeMOF NPs as platforms by directly reducing HAuCl4 in water using sodium borohydride as a reductant. As shown in Figure 1b,d, dark spots corresponding to the Au NPs ≈5 nm in diameter were observed on the exterior surface of Au/FeMOF NPs. 1451

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5352 440 PEG-Au/FeMOF@CPT NPs Cancer Therapy
5351 440 PEG-Au/FeMOF@CPT NPs Cancer Therapy Triggered by the high concentration of phosphate inside the cancer cells, Au/FeMOF@CPT NPs effectively collapse after internalization, resulting in the complete drug release and activation of the cascade catalytic reactions.

References

ref title DOI material type comment
3628 440 A Nanomedicine Fabricated from Gold Nanoparticles‐Decorated Metal–Organic Framework for Cascade Chemo/Chemodynamic Cancer Therapy https://doi.org/10.1002/advs.202001060 Composite metal–organic framework (MOF) nanoparticles and gold nanoparticles (Au NPs)(PEG-Au/FeMOF@CPT NPs)