hemin@CD

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7470 181 hemin@CD 2.3 nm TEM High-resolution TEM image shows the lattice fringe of 0.21 nm corresponding to the (100) facet (inset of Fig. 1a) [27]. After hemin was modified on CDs, the average size of hemin@CDs is 2.3 nm (Fig. 1b), which suggests there have been no significant change in the average size of CDs after hemin molecule decoration.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6073 181 hemin@CD POD phenol 0.031 mM 181 Fig. S4 shows that the apparent Km values with phenol, 4-APP and H2O2 are 0.031 mM, 0.011 mM, and 0.30 mM, respectively. The apparent Km value of hemin@CDs with phenol is lower than that of HRP (5 mM) [32], suggesting higher affinity for phenol.
6074 181 hemin@CD POD 4-APP 0.011 mM 181 181
6075 181 hemin@CD POD H2O2 0.3 mM 181 181

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5091 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples glucose Fluor 0.17–133 μM 0.15 μM 92.2%~105.6%
5092 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples xanthine Fluor 0.17–33 μM 0.12 μM 98.8-103.6%
5093 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples xanthine Color 0.17–33 μM 0.15 μM 93.4-102.4%
5094 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples H2O2 Fluor 0.17–133 μM 0.15 μM
5095 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples glucose Color 0.17–133 μM 0.15 μM 92.2%~105.6%
5096 181 hemin@CD a colorimetric and fluorescent dual-channel sensor for H2O2, glucose and xanthine was developed, and the results are satisfied in the application of real samples H2O2 Color 0.17–133 μM 0.11 μM

References

ref title DOI material type comment
3412 181 Hemin@carbon dot hybrid nanozymes with peroxidase mimicking properties for dual (colorimetric and fluorometric) sensing of hydrogen peroxide, glucose and xanthine https://doi.org/10.1007/s00604-019-4103-4 Composite hemin@carbon dot hybrid nanozymes (hemin@CD)