organic nanozymes

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7554 311 organic nanozymes TEM As imaged with TEM, the freshly prepared nanozymes show uniform and small diameters of about 3 nm (Figure 2a), and upon exposure to the radicals, for example, H2O2 or •OH (Figure S6a), they aggregated gradually to about 300 nm because of multiple disulphide bridging between particles. Likewise, the AFM image demonstrates a uniform height of about 3 nm for the nanozyme (Figure 2b). Under H2O2 or •OH treatments (Figure S6b), the nanozyme sizes increase significantly in width with similar morphologies to those in TEM images, but their heights reached only about 10 nm, likely resulting from a collapse of soft-structured nanozyme aggregation.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6192 311 organic nanozymes multi-functionalities TMB/H2O2 311 311

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5203 311 organic nanozymes prevent oxidative damage for TBI therapy to reduce the ROS level in damaged brain tissues

References

ref title DOI material type comment
3510 311 Reactive Oxygen Species-Induced Aggregation of Nanozymes for Neuron Injury. https://doi.org/10.1021/acsami.9b17509 Others Herein, we developed an ultrasmall organic nanozyme that can induce significant aggregation under an ROS-rich environment, and it can be used as natural targeting nanozymes to injury sites of the brain trauma.