Core-shell Au@ Co-Fe hybrid nanoparticles as peroxidase mimetic nanozyme for antibacterial application

References

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DOI
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446Core-shell Au@ Co-Fe hybrid nanoparticles as peroxidase mimetic nanozyme for antibacterial applicationhttps://doi.org/10.1016/j.procbio.2020.05.003CompositeCore-shell Au@Co-Fe hybrid nanoparticles

Materials

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size
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BET
b nanozyme
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446Au@Co-Fe NPs25nmTEMThe TEM image also confirmed that Au@Co-Fe NPs are spherical and about 25 nm.253U/mgThe Au@Co-Fe NPs activity (units) calculated based on the Eq. 4:(4)bnanozyme=Vε×l×(ΔAΔt) In the Eq. 4, b nanozyme is the catalytic activity of Au@Co-Fe NPs defined in units. V is the total volume of reaction solution (μl), ε is the molar extinction coefficient (39,000 M−1 cm−1) of the oxidized TMB, at 652 nm, l is the path length of light traveling in the cuvette (cm), A is the absorbance after subtraction of the blank value and ΔA/Δt is the initial rate of change in absorbance at 652 nm min−1.
446Au22.40.8nmDLS31U/mg
446CoCl218U/mg
446FeSO426U/mg
446FeSO4+ CoCl230U/mg
446Au@Co NPs36U/mg
446Au@Fe NPs72U/mg
446HRP natural153U/mg
446HRP natural517U/mg
446Au@Co-Fe NPs53.41.8nmDLSMean diameter87U/mg

Kinetics

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kcat/km 10n
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comment
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Applications

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446Au@Co-Fe NPsantibacterial