Construction and characterization of magnetic cascade metal-organic framework/enzyme hybrid nanoreactors with enhanced effect on killing cancer cells

References

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title
DOI
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839Construction and characterization of magnetic cascade metal-organic framework/enzyme hybrid nanoreactors with enhanced effect on killing cancer cellshttps://doi.org/10.1016/j.colsurfa.2020.124990Compositemagnetic metal-organic framework (zeolitic imidazolate framework 8, ZIF-8) nanoparticles (NPs) with ferrimagnetic structures inside loaded with GOx(Fe@ZIF-8@GOx NRs)

Materials

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BET
b nanozyme
b 10n
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sa 10n
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839Fe@ZIF-8@GOx NRs635180nmDLSThe obtained Fe@ZIF-8@GOx NRs showed an average size of 635 ± 180 nm in DMEM/10%FBS, which is larger than that measured from SEM images.

Kinetics

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vmax
vmax err
vmax 10n
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kcat
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kcat 10n
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kcat/km
kcat/km 10n
kcat/km unit
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839Fe@ZIF-8@GOx NRscascade reactionGlucose11.04mM3.35-8M/s839

Applications

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linear range
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839Fe@ZIF-8@GOx NRskill cancer cells