A simple chemiluminescent aptasensor for the detection of α-fetoprotein based on iron-based metal organic frameworks

References

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345A simple chemiluminescent aptasensor for the detection of α-fetoprotein based on iron-based metal organic frameworkshttps://doi.org/10.1039/C9NJ05870BMOFThree iron-based metal organic frameworks (Fe-MOFs) were prepared and compared.Among Fe-MOFs, MIL-100 (Fe) showed the highest catalytic activity.

Materials

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BET
b nanozyme
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345MIL-53 (Fe)less than 250 nmnmSEM

Kinetics

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Applications

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345MIL-100 (Fe)The aptasensor showed a wide linear range of 1.0 × 10−10 g L−1 to 3.0 × 10−5 g L−1 and a low detection limit of 7.7 × 10−11 g L−1. The aptasensor also showed excellent selectivity and sensitivity. The novel sensing platform could provide a potential alternative method for AFP detection in simple samples.CL1E-10-3E−5g/L7.7 × 10−11g/L