Multimodal theranostics augmented by transmembrane polymer-sealed nano-enzymatic porous MoS2 nanoflowers

References

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title
DOI
material type
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849Multimodal theranostics augmented by transmembrane polymer-sealed nano-enzymatic porous MoS2 nanoflowershttps://doi.org/10.1016/j.ijpharm.2020.119606CompositeDOX-loaded MoS2 nanoflowers(DMNF/DMNS) and PPL-coated MoS2 nanoflowers(MNFPPL)

Materials

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size
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BET
b nanozyme
b 10n
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specific act
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849DMNF/DMNS and MNFPPL31515nmTEMMNF was spiny nanoparticle (about 300 nm ~ 330 nm) assembled by 3D-stacking nanosheets with porous structure.

Kinetics

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T
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kcat
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comment
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Applications

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linear range
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849DMNF/DMNS and MNFPPLstably deliver anticancer drug doxorubicin (DOX) into the tumor cells for pH/NIR-responsive chemotherapy, provid strong photoacoustic, photothermal performances and stimulated generation of reactive oxygen species (ROS) for imaging-guided PTT/PDT/CDT combined therapy.