ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury

References

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title
DOI
material type
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42ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injuryhttps://doi.org/10.7150/thno.40395CompositeCeria nanoparticles were modified with triphenylphosphine (TCeria NPs), followed by coating with ROS-responsive organic polymer (mPEG-TK-PLGA) and loaded atorvastatin (Atv/PTP-TCeria NPs)

Materials

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material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
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42Atv/PTP-TCeria NPs8.161.98nmTEMthe average sizes 8.16±1.98 nmU/mg

Kinetics

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pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
42Atv/PTP-TCeria NPsSODH2O24242

Applications

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material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
42Atv/PTP-TCeria NPsthe sepsis-induced AKI therapyROSUnsure