Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healing

References

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title
DOI
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221Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healinghttps://doi.org/10.1007/s11427-019-9590-6CompositeVitamin B2(VB2) functionalized iron oxide nanozymes(IONzymes)

Materials

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material
size
size err
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size comment
BET
b nanozyme
b 10n
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specific act
sa 10n
sa unit
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221VB2-IONzymes<200nmSEMThe naked IONzymes showed a spherical shape with a diameter of about 200 nm. VB2-IONzymes became smaller and developed a rough surfaceupon modification with a high amount of VB2.

Kinetics

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enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
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vmax 10n
vmax unit
kcat
kcat err
kcat 10n
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kcat/km
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kcat/km unit
comment
221VB2-IONzymesPODTMB4.5555.4mM627.0nM/s221It was observed that 0.5 g of VB2-modified IONzymes had a greater increase in Vmax/Km ratio than naked IONzymes (3.7- and 8.8-fold, respectively). These results indicated that VB2 modification significantly improve the peroxidase-like activity of IONzymes.
221VB2-IONzymesPODH2O24.5342.3mM261.4nM/s221221

Applications

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application
target
method
linear range
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LOD
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recovery
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221VB2-IONzymesmouth ulcer healing