Nanozyme Database

	ref	title	DOI	material type	comment
4054	868	An Ultrasmall RuO2 Nanozyme Exhibiting Multienzyme-like Activity for the Prevention of Acute Kidney Injury	https://doi.org/10.1021/acsami.0c07886	Metal oxide	the ultrasmall RuO2NPs promising as a nanozyme for the prevention of AKI

	ref	material	size	size err	size unit	size type	size comment	BET	b _nanozyme	b 10ⁿ	b unit	specific act	sa 10ⁿ	sa unit	comment
8063	868	RuO2	2		nm	TEM	the mean diameter of the RuO2NPs was ∼2 nm, and the hydrodynamic size of RuO2NPs was about 5.4 nm

	ref	material	enzyme type	substrate	pH	T	k_m	k_m err	k_m 10ⁿ	k_m unit	v_max	v_max err	v_max 10ⁿ	v_max unit	k_cat	k_cat err	k_cat 10ⁿ	k_cat unit	k_cat/k_m	k_cat/k_m 10ⁿ	k_cat/k_m unit	comment
6763	868	RuO2	CAT	H2O2			3.59			mM	2.29			mM/min					868

	ref	material	application	target	method	linear range	linear ran unit	LOD	lod unit	recovery	comment
5795	868	RuO2	The NP catalytic properties mimic the activity of catalase, peroxidase, superoxide dismutase, and glutathione peroxidase. The nanozyme can be efficiently and rapidly absorbed by human embryonic kidney cells while significantly reducing ROS-induced apoptosis by eliminating excess ROS. After intravenous injection, the ultrasmall RuO2NPs significantly inhibit the development of AKI in mice. In vivo toxicity experiments demonstrate the biosafety of the NPs after long-term preventing.	ROS