Multi-enzyme mimetic ultrasmall iridium nanozymes as reactive oxygen/nitrogen species scavengers for acute kidney injury management

References

ref title DOI material type comment
4181 995 Multi-enzyme mimetic ultrasmall iridium nanozymes as reactive oxygen/nitrogen species scavengers for acute kidney injury management https://doi.org/10.1016/j.biomaterials.2021.120706 Others In this study, we reported ultrasmall polyvinylpyrrolidone-coated iridium nanoparticles (denoted as Ir NPs-PVP, 1.5 nm) as multi-enzyme mimetic to scavenge a variety of RONS, offering an efficient RONS-induced cellular protection.

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6912 995 NPs-PVP CAT H2O2 7.4 25 43.4 mM 60 -3 mM/s 995
6907 995 Pt@PEG CAT H2O2 2-11 20-80 21.32 mM 0.071 -6 M/s 995

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5902 995 NPs-PVP Acute kidney injury management