Stimuli-Responsive Small-on-Large Nanoradiosensitizer for Enhanced Tumor Penetration and Radiotherapy Sensitization

References

ref title DOI material type comment
3430 199 Stimuli-Responsive Small-on-Large Nanoradiosensitizer for Enhanced Tumor Penetration and Radiotherapy Sensitization https://doi.org/10.1021/acsnano.0c03094 Composite disassembled small-on-large molybdenum disulfide/hafnium dioxide (MoS2/HfO2) dextran (M/H-D) nanoradiosensitizer.

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7485 199 HfO2 NPs 10 nm TEM The size of HfO2 NPs (2–5 nm) anchored on the surface of MoS2 was smaller than the HfO2 NPs alone (10 nm), which could be attributed to the two different nucleation centers of HfO2 in the presence or absence of MoS2 NSs in the solution.
7484 199 HfO2 NPs 2~5 nm TEM The size of HfO2 NPs (2–5 nm) anchored on the surface of MoS2 was smaller than the HfO2 NPs alone (10 nm), which could be attributed to the two different nucleation centers of HfO2 in the presence or absence of MoS2 NSs in the solution.
7483 199 M/H-D 213.2 15.8 nm DLS After the modification of dextran, dynamic light scattering (DLS) measurements showed the average hydrous dynamic diameter of 70% of the M/H-D was ∼213.2 ± 15.8 nm (Figure S2).
7482 199 MoS2 100-200 nm TEM a layered structure with approximately average size (the longest part) of 100–200 nm and uniform edges.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5109 199 M/H-D Enhanced Tumor Penetration and Radiotherapy Sensitization