Multienzyme‐Mimic Ultrafine Alloyed Nanoparticles in Metal Organic Frameworks for Enhanced Chemodynamic Therapy

References

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ref
title
DOI
material type
comment
1121Multienzyme‐Mimic Ultrafine Alloyed Nanoparticles in Metal Organic Frameworks for Enhanced Chemodynamic Therapyhttps://doi.org/10.1002/smll.202005865MOFPEG modified Cu-Pd@MIL-101 (Cu-Pd@MIL-101-PEG, CPMP)

Materials

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material
size
size err
size unit
size type
size comment
BET
b nanozyme
b 10n
b unit
specific act
sa 10n
sa unit
comment
1121CPMP330nmTEMIt can be seen from Figure S3, Supporting Information, that 9.5% CPMP had an average particle size of about 330 nm with good dispersity (the polydispersity index of 9.5% CPMP in water and phosphate buffer solution [PBS], as well as cell medium is 0.221, 0.213, and 0.116, respectively), which is suitable for biological applications and can achieve good therapeutic results.

Kinetics

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material
enzyme type
substrate
pH
T
km
km err
km 10n
km unit
vmax
vmax err
vmax 10n
vmax unit
kcat
kcat err
kcat 10n
kcat unit
kcat/km
kcat/km 10n
kcat/km unit
comment
1121CPMPPODTMB1.1-5M7.4-8M/s1121
1121CPMPPODH2O22.5-5M8.3-8M/s1121

Applications

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material
application
target
method
linear range
linear ran unit
LOD
lod unit
recovery
comment
1121CPMPtumor chemodynamic therapy