Near‐Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple‐Therapy for Combating Multidrug‐Resistant Bacterial Infections via Oxygen‐Vacancy Molybdenum Trioxide Nanodots

References

ref title DOI material type comment
3804 618 Near‐Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple‐Therapy for Combating Multidrug‐Resistant Bacterial Infections via Oxygen‐Vacancy Molybdenum Trioxide Nanodots https://doi.org/10.1002/smll.202005739 Metal oxide oxygen-vacancy molybdenum trioxide nanodots (MoO3−x NDs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7841 618 MoO3−x NDs The typical transmission electron microscopy (TEM) image of the as-obtained supernatant (Figure 1A) showed well-dispersed nanodots with an average diameter of 3.07 ± 0.35 nm (Figure 1B) as calculated from counting 80 particles of the TEM images. The high-resolution TEM (HRTEM) characterization showed the lattice spacings of about 0.231 nm in the crystal structure of the nanodots, which was consistent well with the (224) diffraction planes of MoO3 (JCPDS No. 21-0569). As indicated in the Figure 1C, the atomic force microscope (AFM) image with the height analysis (inset of Figure 1C) confirmed the good mono-dispersibility of the nanodots. The average height was 1.43 ± 0.08 nm,

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6504 618 MoO3−x NDs POD TMB 2.65 mM 0.0152 -7 M/s 618 618
6503 618 MoO3−x NDs POD H2O2 0.26 mM 1.52 -7 M/s 618 618

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5555 618 MoO3−x NDs Near-Infrared Regulated Nanozymatic/Photothermal/Photodynamic Triple-Therapy for Combating Multidrug-Resistant Bacterial Infections