Isolation and Detection of Exosomes Using Fe2O3 Nanoparticles

References

ref title DOI material type comment
4330 1145 Isolation and Detection of Exosomes Using Fe2O3 Nanoparticles https://doi.org/10.1021/acsanm.0c02807 Metal oxide carboxyl group-functionalized iron oxide nanoparticles (C-IONPs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8198 1145 C-IONPs 250 nm TEM On the other hand, DLS analysis also revealed uniform hydrodynamic size distribution of the nanoparticles. The hydrodynamic radius of the C-IONPs was found to be 318.4 ± 13.58 nm with a polydispersity of 41.25% ± 6.86 (Figure S4).

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
7109 1145 C-IONPs POD TMB 0.0992 mM 0.156 -8 M/s 1.04 × 10–4 1145
7108 1145 C-IONPs POD H2O2 114 mM 0.197 -8 M/s 1.31 × 10–4 1145

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
6044 1145 C-IONPs exhibits an excellent specificity for OVCAR3 cell-derived exosomes exosome E-chem 6.25 × 10^5-1.0 × 10^7 exosomes/mL 1.25 × 10^6 exosomes/mL