Nanoceria-Based Phospholipase-Mimetic Cell Membrane Disruptive Antibiofilm Agents

References

ref title DOI material type comment
4539 1378 Nanoceria-Based Phospholipase-Mimetic Cell Membrane Disruptive Antibiofilm Agents https://doi.org/10.1021/acsabm.0c00363 Composite polymer-coated nanoceria (PAA-Cnp)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8394 1378 PAA-Cnp 10 nm TEM The scanning electron microscopy (SEM) images of the nanomaterials showed agglomerated particles, which upon sonication in acetone revealed a particle-like morphology (size ∼10 nm) in the transmission electron microscopy (TEM) images

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
7289 1378 Cnp hydrolase NPPC 7.8 37 9.8 0.25 mM 456 84 µM/h 1378 1378
7288 1378 PAA-Cnp hydrolase NPPC 7.8 37 171.8 1.89 mM 492 68.4 µM/h 1378 1378

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
6232 1378 PAA-Cnp membrane disruption-based bactericidal activity against a broad spectrum of pathogenic as well as biofilm-encased bacteria