A simple chemiluminescent aptasensor for the detection of α-fetoprotein based on iron-based metal organic frameworks

References

ref title DOI material type comment
3541 345 A simple chemiluminescent aptasensor for the detection of α-fetoprotein based on iron-based metal organic frameworks https://doi.org/10.1039/C9NJ05870B MOF Three iron-based metal organic frameworks (Fe-MOFs) were prepared and compared.Among Fe-MOFs, MIL-100 (Fe) showed the highest catalytic activity.

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7585 345 MIL-53 (Fe) less than 250 nm nm SEM

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5250 345 MIL-100 (Fe) The aptasensor showed a wide linear range of 1.0 × 10−10 g L−1 to 3.0 × 10−5 g L−1 and a low detection limit of 7.7 × 10−11 g L−1. The aptasensor also showed excellent selectivity and sensitivity. The novel sensing platform could provide a potential alternative method for AFP detection in simple samples. CL 1E-10-3E−5 g/L 7.7 × 10−11 g/L