ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury

References

ref title DOI material type comment
3273 42 ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury https://doi.org/10.7150/thno.40395 Composite Ceria nanoparticles were modified with triphenylphosphine (TCeria NPs), followed by coating with ROS-responsive organic polymer (mPEG-TK-PLGA) and loaded atorvastatin (Atv/PTP-TCeria NPs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7361 42 Atv/PTP-TCeria NPs 8.16 1.98 nm TEM the average sizes 8.16±1.98 nm U/mg

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
5937 42 Atv/PTP-TCeria NPs SOD H2O2 42 42

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
4974 42 Atv/PTP-TCeria NPs the sepsis-induced AKI therapy ROS Unsure