Multimodal theranostics augmented by transmembrane polymer-sealed nano-enzymatic porous MoS2 nanoflowers

References

ref title DOI material type comment
4035 849 Multimodal theranostics augmented by transmembrane polymer-sealed nano-enzymatic porous MoS2 nanoflowers https://doi.org/10.1016/j.ijpharm.2020.119606 Composite DOX-loaded MoS2 nanoflowers(DMNF/DMNS) and PPL-coated MoS2 nanoflowers(MNFPPL)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8045 849 DMNF/DMNS and MNFPPL 315 15 nm TEM MNF was spiny nanoparticle (about 300 nm ~ 330 nm) assembled by 3D-stacking nanosheets with porous structure.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5776 849 DMNF/DMNS and MNFPPL stably deliver anticancer drug doxorubicin (DOX) into the tumor cells for pH/NIR-responsive chemotherapy, provid strong photoacoustic, photothermal performances and stimulated generation of reactive oxygen species (ROS) for imaging-guided PTT/PDT/CDT combined therapy.