GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy

References

ref title DOI material type comment
3388 157 GSH‐Depleted Nanozymes with Hyperthermia‐Enhanced Dual Enzyme‐Mimic Activities for Tumor Nanocatalytic Therapy https://doi.org/10.1002/adma.202002439. Composite PEG/Ce-Bi@DMSN

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7449 157 Bi2S3@DMSN 65.6 9.2 nm TEM width 201.32
7448 157 Bi2S3@DMSN 110.6 18.6 nm TEM length
7447 157 PEG/Ce-Bi@DMSN 3-4 nm TEM The TEM image of the CeO2 nanozymes presented in Figure 1d, shows that the CeO2 nanozymes were 3–4 nm in diameter and were suitable for loading into the large-pore channels of Bi2S3@ DMSN nanoparticles

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6039 157 PEG/Ce-Bi@DMSN CAT H2O2 50 70.5 mM 0.71 mg/Lmin 157 at 50 ℃ Vmax unit mg/Lmin
6038 157 PEG/Ce-Bi@DMSN CAT H2O2 25 84.8 mM 0.48 mg/Lmin 157 at 25 ℃ Vmax unit mg/Lmin
6037 157 PEG/Ce-Bi@DMSN POD H2O2 25 32.11 mM 2.63 -8 M/s 157
6036 157 PEG/Ce-Bi@DMSN POD H2O2 50 27.54 mM 3.85 -8 M/s 157

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5062 157 PEG/Ce-Bi@DMSN in vitro photothermal-enhanced nanocatalytic therapeutic efficacy