ref | title | DOI | material type | comment | |
---|---|---|---|---|---|
3544 | 348 | A biomimetic nanozyme/camptothecin hybrid system for synergistically enhanced radiotherapy | https://doi.org/10.1039/D0TB00676A | Others | camptothecin (CPT)-loaded hollow MnO2 core and an external tumor cell membrane.Cancer cell membranes coated MC nanoparticles (CMC) |
ref | material | size | size err | size unit | size type | size comment | BET | b nanozyme | b 10n | b unit | specific act | sa 10n | sa unit | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7587 | 348 | CMC | 112.6 | 4.2 | nm | TEM |
ref | material | enzyme type | substrate | pH | T | km | km err | km 10n | km unit | vmax | vmax err | vmax 10n | vmax unit | kcat | kcat err | kcat 10n | kcat unit | kcat/km | kcat/km 10n | kcat/km unit | comment |
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ref | material | application | target | method | linear range | linear ran unit | LOD | lod unit | recovery | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|
5252 | 348 | CMC | The anti-tumor mechanism of this system includes two aspects: (i) the generated oxygen can improve the hypoxic state of the tumor microenvironment and enhance the radiotherapy sensitivity and (ii) CPT can induce cell cycle arrest in the S-phase at a low dose, which further increases the radio-sensitivity of tumor cells and augmented radiation-induced tumor damage. |