Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease model

References

ref title DOI material type comment
3308 77 Mitochondria-targeted TPP-MoS2 with dual enzyme activity provides efficient neuroprotection through M1/M2 microglial polarization in an Alzheimer's disease model https://doi.org/10.1016/j.biomaterials.2019.119752 Composite TPP-conjugated 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] functionalized molybdenum disulfide quantum dots (TPP-MoS2 QDs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7383 77 TPP-MoS2 QDs 50 nm TEM the lateral diameters
7382 77 TPP-MoS2 QDs 1.69 0.15 nm TEM the thicknesses

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
4993 77 TPP-MoS2 QDs mitigate AD pathology O2•- •OH H2O2