ref | title | DOI | material type | comment | |
---|---|---|---|---|---|
4367 | 1182 | Glycoengineering Artificial Receptors for Microglia to Phagocytose Aβ aggregates | https://doi.org/10.1039/D0SC07067J | MOF | n-porphyrin metal–organic frameworks (Mn-MOFs) with superoxide dismutase (SOD) and catalase (CAT) mimic activity are employed to carry N-azidoacetylmannosamine (AcManNAz) , AcManNAz@Mn-MOFs (Az@MOF) |
ref | material | size | size err | size unit | size type | size comment | BET | b nanozyme | b 10n | b unit | specific act | sa 10n | sa unit | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
8224 | 1182 | Az@MOF | Scanning electron microscopy (SEM) imaging indicated the extremely homogeneous morphology with a length of 200 nm and a width of 75 nm (Fig. 1a). Furthermore, transmission electron microscopy (TEM) images of Mn-MOFs in Fig. 1b directly displayed a pore size of 1.25 nm, which is in accordance with the result of N2 adsorption–desorption (1.25 nm) in Fig. S7.† The pore size of 1.25 nm permitted the encapsulation and release of AcManNAz (MW = 430). |
ref | material | enzyme type | substrate | pH | T | km | km err | km 10n | km unit | vmax | vmax err | vmax 10n | vmax unit | kcat | kcat err | kcat 10n | kcat unit | kcat/km | kcat/km 10n | kcat/km unit | comment |
---|
ref | material | application | target | method | linear range | linear ran unit | LOD | lod unit | recovery | comment | |
---|---|---|---|---|---|---|---|---|---|---|---|
6071 | 1182 | Az@MOF | eradicate over-expressed reactive oxygen species, synergistically promote the phagocytosis and clearance of Aβ with significantly enhanced activity and negligible adverse effects |