Nanozyme Database

	ref	title	DOI	material type	comment
3396	165	Dual modality sensor using liposome-based signal amplification technique for ultrasensitive norovirus detection	https://doi.org/10.1016/j.bios.2020.112169	Metal oxide	V2O5 nanoparticles-encapsulated liposomes (VONP-LPs)

	ref	material	size	size err	size unit	size type	size comment	BET	b _nanozyme	b 10ⁿ	b unit	specific act	sa 10ⁿ	sa unit	comment
7457	165	VONP-LPs	25	1.5	nm	TEM	the particle size distribution of V2O5 NPs in the range of 15–40 nm with average lateral size of 25 � 1.5 nm.

	ref	material	enzyme type	substrate	pH	T	k_m	k_m err	k_m 10ⁿ	k_m unit	v_max	v_max err	v_max 10ⁿ	v_max unit	k_cat	k_cat err	k_cat 10ⁿ	k_cat unit	k_cat/k_m	k_cat/k_m 10ⁿ	k_cat/k_m unit	comment
6053	165	VONP-LPs	POD	H2O2			0.04			mM	20.9		-1	μM/min					165		M-1 s-1
6052	165	VONP-LPs	POD	TMB			0.02			mM	19.7		-1	μM/min					165		M-1 s-1	165

	ref	material	application	target	method	linear range	linear ran unit	LOD	lod unit	recovery	comment
5072	165	VONP-LPs	To determine the linear range and sensitivity of the developed dualmodality sensor, different concentrations of NoV-LPs are examined. Anti-NoV antibody-conjugated VONP-LPs, MNPs and aliquot of NoV-LPs with various concentrations are mixed. VONP-LPs and the MNPs are bound with NoV-LPs through the specific interaction with antibody on their surface and a nanoconjugate of VONP-LPs, NoV-LPs and MNPs is formed.	NoV-LPs	Color	10-108	fg/ml	4.1	fg/ml
5071	165	VONP-LPs	Above results confirmed the ultra sensitivity and excellent specificity of the VONP-LPs based dual-modality biosensor proving applicability of developed sensor for real samples (Fig. 5b). To confirm the practicability real clinical samples are examined. Different types of clinical NoV (GII. 2, GII. 3, GII.4) from human feces of infected patients are detected using the developed dual-modality sensor	NoV-LPs and clinical samples	Color	100-107	copies/ml	72	copies/ml