Label-free determination of thyroglobulin using template-probe double imprinted composites

References

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873Label-free determination of thyroglobulin using template-probe double imprinted compositeshttps://doi.org/10.1016/j.snb.2020.128028Carbona novel approach to synthesize molecular imprinting polymers (MIPs)/hemin-graphene nanosheets (H-GNs) composites on the paper, using Tg and 3,3′,5,5′-tetramethylbenzidine (TMB, probe) as double templates

Materials

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BET
b nanozyme
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specific act
sa 10n
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873H-GNsXPSThe XPS of the synthesized material further illustrated the construction of MIP composites. Fe2p signals (1.59%) and N1s peak at 398.1 eV of H-GNs/paper were observed, indicating the presence of hemin.

Kinetics

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vmax
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vmax 10n
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kcat/km unit
comment
873H-GNsOXDTMB873
873H-GNsOXDH2O21.25mM16.7-8M/s873

Applications

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linear range
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873H-GNsIt was supposed to be applied for Tg determination in serum to evaluate persistent or recurrent differentiated thyroid carcinoma.Thyroglobulin (Tg)0.7-100ng/mL0.1ng/mL