Minimal metallo-nanozymes constructed through amino acid coordinated self-assembly for hydrolase-like catalysis

References

ref title DOI material type comment
3859 673 Minimal metallo-nanozymes constructed through amino acid coordinated self-assembly for hydrolase-like catalysis https://doi.org/10.1016/j.cej.2020.124987 Composite Herein, we report the construction of minimal metallo-nanozymes through amino acid coordinated self-assembly by using amino acid derivatives and zinc (II) ions as the building blocks, reminiscent of the components of the catalytic architectures in natural hydrolases

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7890 673 metallo-nanozymes 175.8 41.7 nm DLS TEM image showed that the formed metallo-nanozymes have a spherical morphology with a size of 170 nm (Fig. 1a), which is in agreement with the result obtained from dynamic light scattering (DLS) (175.8 ± 41.7 nm) (Fig. 1b).

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6567 673 metallo-nanozymes hydrolase 673

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5603 673 metallo-nanozymes This work highlights the minimal principle and excellent catalytic performance of stable metallo-nanozymes, opening up immense opportunities in the development of highly efficient nanozymes and catalytic prodrug conversion.