Multienzyme‐Mimic Ultrafine Alloyed Nanoparticles in Metal Organic Frameworks for Enhanced Chemodynamic Therapy

References

ref title DOI material type comment
4308 1121 Multienzyme‐Mimic Ultrafine Alloyed Nanoparticles in Metal Organic Frameworks for Enhanced Chemodynamic Therapy https://doi.org/10.1002/smll.202005865 MOF PEG modified Cu-Pd@MIL-101 (Cu-Pd@MIL-101-PEG, CPMP)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8184 1121 CPMP 330 nm TEM It can be seen from Figure S3, Supporting Information, that 9.5% CPMP had an average particle size of about 330 nm with good dispersity (the polydispersity index of 9.5% CPMP in water and phosphate buffer solution [PBS], as well as cell medium is 0.221, 0.213, and 0.116, respectively), which is suitable for biological applications and can achieve good therapeutic results.

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
7092 1121 CPMP POD TMB 1.1 -5 M 7.4 -8 M/s 1121
7091 1121 CPMP POD H2O2 2.5 -5 M 8.3 -8 M/s 1121

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
6028 1121 CPMP tumor chemodynamic therapy