Synergistic in-situ growth of silver nanoparticles with nanozyme activity for dual-mode biosensing and cancer theranostics

References

ref title DOI material type comment
4505 1342 Synergistic in-situ growth of silver nanoparticles with nanozyme activity for dual-mode biosensing and cancer theranostics https://doi.org/10.1016/j.cclet.2020.09.013 Composite AgNPs@GQDs is prepared by synergistic in-situ growth of silver nanoparticles (AgNPs) on the complex of tannic acid (TA) and graphene quantum dots (GQDs)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
8347 1342 AgNPs@GQDs 14-24 nm TEM In comparison, AgNPs without the assembly of GQDs show the morphology with a little aggregation (Fig. S1 in Supporting information), which are smaller than that of AgNPs@GQDs (14−24 nm). Upon treating with H2O2, the characteristic nanoparticles of AgNPs@GQDs disappear, and the monodisperse nanodots with the average diameter of 6.7 nm are observed in TEM image 25.3479
8346 1342 GQDs 6.4 nm TEM Transmission electron microscopy (TEM) images of GQDs demonstrate a good monodispersity with the average diameter of 6.4 nm in lateral size (Fig. 1B).

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
7259 1342 GQDs POD TMB 1.84 mM 0.0117 ΔAbs/s 1342 1342

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
6193 1342 AgNPs@GQDs detection of glucose glucose Fluor 5-100 μM 1.31 μM
6192 1342 AgNPs@GQDs detection of glucose glucose Color 0.5-50 μM 0.17 μM 92.89%–104.44%
6191 1342 AgNPs@GQDs detection of H2O2 H2O2 Fluor 2-60 μM 0.83 μM
6190 1342 AgNPs@GQDs detection of H2O2 H2O2 Color 0.08-40 μM 0.025 μM