Remote-controlled multi-enzyme system for enhanced tumor therapy via dark/light relay catalysis

References

ref title DOI material type comment
3417 186 Remote-controlled multi-enzyme system for enhanced tumor therapy via dark/light relay catalysis https://doi.org/10.1039/C9NH00583H Composite Membrane camouflaged and GOx loaded hollow mesoporous Prussian blue (mGPB)

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7475 186 mGPB ~182 nm TEM After loading, the hydrodynamic size of the nanoparticles (162.2 nm) increased to ∼182.0 nm

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6080 186 mGPB POD H2O2 8.66 mM 5.03 -8 M/s 186 186
6079 186 mGPB POD glucose 4.51 mM 3.94 -8 M/s 186

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5102 186 mGPB a multi-enzyme system (mGPB) with self-sufficient H2O2 supply and photoselective multienzyme-like activities was developed for enhanced tumor catalytic therapy