Protein-Supported RuO2 Nanoparticles with Improved Catalytic Activity, In Vitro Salt Resistance, and Biocompatibility: Colorimetric and Electrochemical Biosensing of Cellular H2O2

References

ref title DOI material type comment
3440 209 Protein-Supported RuO2 Nanoparticles with Improved Catalytic Activity, In Vitro Salt Resistance, and Biocompatibility: Colorimetric and Electrochemical Biosensing of Cellular H2O2 https://doi.org/10.1021/acsami.0c00778 Metal oxide RuO2NP synthesis (BSA-RuO2NPs) supported by bovine serum albumin (BSA).

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment
7493 209 BSA-RuO2NPs 7 nm TEM As can be seen in Figure 1C, size distribution analysis of 100 random BSA-RuO2NPs by Gaussian fitting, the particle size has been calculated to be ∼7 nm. 710 U/g

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6106 209 BSA-RuO2NPs POD TMB 0.034 mM 5.54 -7 M/s 0.83 3 1/s 209 7 M-1 s-1
6105 209 BSA-RuO2NPs POD H2O2 189.42 mM 3.76 -7 M/s 0.57 3 1/s 209 3 M-1 s-1

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5122 209 BSA-RuO2NPs monitoring in situ H2O2 secretion from living MCF-7 cells. H2O2 Color 2-800 μM 1.8 μM
5121 209 BSA-RuO2NPs monitoring in situ H2O2 secretion from living MCF-7 cells. H2O2 E-chem 0.4-3850 μM 0.18 μM