An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging

References

ref title DOI material type comment
3638 450 An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging https://doi.org/10.1126/sciadv.abb1421 Composite copper cluster firmly anchored in bovine serum albumin conjugated with tumor-targeting peptide

Materials

ref material size size err size unit size type size comment BET b nanozyme b 10n b unit specific act sa 10n sa unit comment

Kinetics

ref material enzyme type substrate pH T km km err km 10n km unit vmax vmax err vmax 10n vmax unit kcat kcat err kcat 10n kcat unit kcat/km kcat/km 10n kcat/km unit comment
6305 450 RGD-BSA-CuCs POD Amplex UltraRed 7.4 1.22 0.14 -3 M 7.85 0.33 -9 M/s 6.38 0.27 -4 1/s 450
6304 450 RGD-BSA-CuCs POD Amplex UltraRed 6.5 3.87 0.17 -4 M 1.24 0.18 -9 M/s 1.01 0.14 -4 1/s 450 450

Applications

ref material application target method linear range linear ran unit LOD lod unit recovery comment
5365 450 RGD-BSA-CuCs catalytic cancer-specific DNA cleavage and operando imaging